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Subject index
A
Angiomatosis, 11, 136, 157, 158, 161,
320, 321
Angiomyofibroblastoma, 10, 47, 71-72
Angiomyolipoma, 10, 19, 29, 36, 128,
129, 221
Angiomyoma, 128
Angiosarcoma, 11, 13, 16, 28, 155,
169, 170, 175-177, 226, 319, 321,
322-323
Angiosarcoma multiplex, 170
APC, see Adenomatous polyposis coli
Arciform calcification, 230
Arteriovenous haemangioma, 156-158
Arteriovenous malformation, 158, 161
Arteriovenous shunt, 158, 160, 161, 175
ASCL2, 355
Askin tumour, 298
ASPL, 209
ASPS, see Alveolar soft part sarcoma
ASPSCR1, 209
Ataxia telangiectasia, 365
ATF1, 195, 212
Atypical decubital fibroplasia, 55
Atypical fibrous histiocytoma, 292
Atypical lipoma, 10, 19, 20, 35, 36, 38,
44, 46, 215
Atypical lipomatous tumour, 10, 19,
35-38, 44, 46, 215
Auditory canal, 146
Beta-catenin, 84
Biphasic synovial sarcoma, 200
Birbeck granules, 346, 347
Bizarre parosteal osteochondromatous
proliferation, 235
BLM, 350
Bloom syndrome, 350, 365, 367
Bone morphogenetic protein-6, 268
Bony implants, 334
Botryoid rhabdomyosarcoma, 146, 148
BRCA1, 364
Budd-Chiari syndrome, 131
Bussey-Gardner polyposis, 352
BWSCR1, 355
BWSCR2, 355
BWSCR3, 355
Abdominal wall defect, 354, 355
Acroangiodermatitis, 158
Acute myelogenous leukaemia, 308,
367
Adamantinoma, 226, 230, 231, 325,
332-334, 343, 344
Adenomatous polyposis coli, 76, 84,
350, 352, 353
Adipocytic liposarcoma, 35
Adrenocortical carcinoma, 354
Adult fibrosarcoma, 10, 100-101, 107
Adult rhabdomyoma, 142
Aggressive fibromatosis, 83
Aggressive infantile fibromatosis, 98
AIDS, 23, 170
Albright hereditary osteodystrophy, 350
ALK, 78, 93
Alpha-1-antichymotrypsin, 121, 347
Alpha-1-antitrypsin, 121, 347
Alveolar rhabdomyosarcoma, 11, 141,
146, 150-152
Alveolar soft part sarcoma, 11, 16,
208-210
ALX4, 361
Anaplastic rhabdomyosarcoma, 146
Aneurysmal bone cyst, 118, 194, 226,
231, 241, 242, 244, 257, 262, 271,
311, 312, 338-339, 341, 348, 358
Aneurysmal bone cyst-like osteo-
sarcoma, 271
Angioglomoid tumour, 173
Angioleiomyoma, 11, 128-129, 135,
138, 326
Angiolipoma, 10, 28, 156, 157, 161
Angiolymphoid hyperplasia with
eosinophilia, 159
Angioma, 156, 159, 239, 320
Angiomatoid fibrous histiocytoma, 11,
14, 185, 194-195
Angiomatoid malignant fibrous histio-
cytoma, 194
C
Café-au-lait spots, 357
Calcifying aponeurotic fibroma, 10, 58-69
Calcifying fibrous pseudotumour, 77
Calcifying fibrous tumour, 10, 77
Calcifying giant cell tumour, 241
Calcifying synovial sarcoma, 201
Cambium layer, 148
cAMP, 187, 212, 357, 358
Capillary haemangioma, 158, 161, 164,
320
Carney complex, 350
Carpal tunnel syndrome, 66
Cathepsin L, 268
Cavernous haemangioma, 156, 157,
177, 320, 356
CCND1, 134, 353
CCND3, 134
CD1a, 346, 347
CD4, 347
CD15, 126, 308
CD20, 126, 148, 165, 304, 308
B
Bannayan-Riley-Ruvalcaba syndrome,
350
BCL2, 80, 84, 85, 87, 90, 202
Beckwith-Wiedemann syndrome, 149,
350, 354-355
Bence-Jones protein, 302
Benign fibrous histiocytoma, 10, 14,
114, 226, 291, 292
Benign fibrous histiocytoma of bone,
292-293
420
Subject index
CD30, 96, 126, 308
CD31, 77, 160, 162, 164, 165, 167, 168,
172, 174, 176, 191, 195, 224, 321, 323
CD34, 32, 34, 56, 67, 69, 72, 74, 76, 77,
78, 80, 85, 87, 89, 90, 95, 96, 99,
101, 105, 106, 115, 133, 137, 139,
160, 162, 164, 165, 167, 168, 172,
174, 176, 187, 190, 191, 193, 195,
202, 206, 220, 224, 245, 321, 323
CD38, 304
CD43, 126
CD45, 111, 113, 126, 346
CD57, 99, 212
CD68, 49, 51, 56, 96, 99, 102, 106, 111,
113, 117, 118, 121, 126, 142, 144,
195, 295
CD79a, 304
CD99, 70, 80, 85, 87, 89, 90, 95, 182,
195, 202, 220, 256, 267, 273, 299
CD117, 93, 133 (see also KIT)
CD138, 304
CD147, 209
CDK4, 37, 122, 134, 151, 268, 276, 281
CDKN1C, 149, 350, 354, 355
CDKN2A, 122, 134, 149, 251, 256, 257,
272, 296, 299, 300, 357
Cellular angiofibroma, 10, 47, 69, 71-74
Cellular myxoma, 186-188
Cementoblastoma, 262
Central chondroma, 237
Central osteogenic sarcoma, 264
Central osteosarcoma, 264, 275, 276
Cervix, 144
CHEK2, 350
Chest wall hamartoma, 226, 348, 354
Chicken wire calcification, 41, 241
Childhood fibrous tumour with
psammoma bodies, 77
Chimeric protein, 26, 151, 195, 218,
299, 300
CHN, 215
Chondroblastic osteosarcoma, 264, 266,
282, 283
Chondroblastoma, 226, 229, 230, 241-
242, 245, 257, 338, 348
Chondrodysplasia, 234, 239, 357
Chondroid chordoma, 315, 316
Chondroid lipoma, 10, 19, 30
Chondroma, 11, 179, 180, 226, 237-240,
249
Chondroma of soft parts, 180
Chondromyxoid fibroma, 226, 243-245
Chondrosarcoma, 11, 179, 181, 213,
214, 226, 227, 231, 238, 239, 240,
245-246, 247-251, 252, 253, 255,
256, 257, 282, 298, 315, 356, 357,
360, 361, 363, 364
Chondrosarcoma with additional
mesenchymal component, 252
CHOP, 37, 42, 122
Chordoid sarcoma, 213
Chordoma, 226, 231, 315-317, 350
Chordoma, familial, 350
Chromosomal instability, 57, 353
Chronic myelogenous leukaemia, 308
Chronic osteomyelitis, 228, 289, 303
Classical osteosarcoma, 264
Clear cell, 221
Clear cell chondrosarcoma,
231, 257-258
Clear cell myomelanocytic tumour
of the falciform ligament /
ligamentum teres, 221
Clear cell sarcoma of soft tissue,
11, 211-212
Coats disease, 363
COL1A2, 26
Collagenous fibroma, 67
Collet-Sicard syndrome, 334
Composite haemangioendothelioma,
11, 165, 168-169
Congenital fibrosarcoma, 98, 99
Congenital fibrosarcoma-like fibro-
matosis, 98
Congenital hypertrophy of the retinal
pigment epithelium, 352
Congenital mesoblastic nephroma,
98, 99
Congenital muscular torticollis, 61
Congenital-infantile fibrosarcoma, 98
Consumption coagulopathy, 158, 163
Conventional osteosarcoma,
264-266, 268, 269, 271-274,
276-278, 281, 283-285
Cortical fibrous dysplasia, 343
Costello syndrome, 350
Cowden disease, 349, 350
Cranial fasciitis, 48, 49
CREBBP, 351
Curvilinear blood vessels, 104
Cyclin D1, 91
Cystic hygroma, 162
D
Dabska tumour, 167
DDIT3, 37, 42, 122
Dedifferentiated chondrosarcoma, 231,
240, 252-254, 358
Dedifferentiated giant cell tumour, 313
Dedifferentiated leiomyosarcomas, 132
Dedifferentiated liposarcoma, 10, 18,
36, 38-39, 43, 44, 46, 102, 120, 122,
125, 126, 215
Deep 'aggressive' angiomyxoma,
189-190
Deep benign fibrous histiocytoma,
114-115
Deep leiomyoma, 11, 130
DEFECT11, 361
Dermatofibrosarcoma, 100, 101, 109
Dermatomyositis, 91
Desmoid tumour, 67, 83, 84, 288, 350,
352, 354
Desmoid tumour of bone, 288
Desmoid-type fibromatosis, 13, 76,
83-84, 92, 352
Desmoplastic fibroblastoma, 10, 47,
66, 67
Desmoplastic fibroma, 226, 275, 280,
287, 288, 290
Desmoplastic fibrosarcoma of infancy,
98
Desmoplastic small round cell tumour,
11, 216-218
Diabetes, 75, 81, 347, 359, 366
Diaphyseal aclasis, 234, 360
Diaphyseal medullary stenosis with
malignant fibrous histiocytoma, 296
Diffuse type giant cell tumour,
111, 112-113
Digital fibrous tumour of childhood, 64
DNA ploidy, 49, 177, 251
Dupuytren contracture, 81
Dupuytren disease, 81
Dysplasia Epiphysealis Hemimelica, 235
E
Ear creases, 354
EBV, see Epstein-Barr virus
E-cadherin, 353
Subject index
421
Ectomesenchymal chondromyxoid
tumour, 198
Ectopic hamartomatous thymoma, 11,
192-193
Elastofibroma, 10, 56-57
Elastofibroma dorsi, 56
EMA, see Epithelial membrane antigen
Embryonal rhabdomyosarcoma, 11, 12,
146-150, 152, 350, 354
Embryonal sarcoma, 146
Embryonic lipoma, 26
EMG syndrome, 354
Enchondroma, 226, 229, 237, 238, 239,
245, 248, 249, 250, 357
Enchondromatosis, 237, 239, 240, 250,
350, 356-357
Endocrinopathies, 357
Eosinophilic granuloma, 345
Epidermoid cyst, 352
Epilepsy, 81
Epiphyseal chondromatous giant cell
tumour, 241
Epithelial membrane antigen, 30, 61, 67,
85, 87, 105, 106, 133, 142, 144,
145, 182, 191, 195, 199, 202, 206,
209, 214, 217, 219, 304, 317, 321,
323, 333
Epithelioid angiosarcoma, 160, 174,
176, 322
Epithelioid haemangioendothelioma,
11, 155, 160, 168, 173-174, 319,
322, 323
Epithelioid haemangioma, 11, 159, 160,
321
Epithelioid sarcoma, 11, 16, 205-207
Epstein-Barr virus, 13, 134
Erdheim-Chester disease, 226, 347
ERG, 299
Essential bone cyst, 340
ETS, 299, 300
ETV1, 299
ETV6, 99, 268
Ewing sarcoma, 13, 16, 182, 185, 218,
225-227, 228, 230, 231, 256, 273,
274, 287, 295, 297, 298-300, 334,
363, 364
EWS, 42, 195, 212, 215, 218, 299, 300
Exomphalos-Macroglossa-Gigantism
syndrome, 354
Exostoses, 234, 235, 360
EXT, 236, 360, 361, 362
EXT1, 235, 236, 350, 360, 361, 362
EXT2, 236, 350, 360, 361, 362
EXT3, 360, 361
EXTL1, 361
EXTL2, 361
EXTL3, 361
Extra-abdominal fibromatoses, 83
Extra-adrenal myelolipoma, 10
Extramedullary plasmacytoma, 302
Extrapulmonary sugar tumour, 221
Extrarenal rhabdoid tumour, 206, 207,
219-220
Extraskeletal chondroma, 180, 181
Extraskeletal myxoid chondrosarcoma,
9, 11, 16, 30, 185, 179, 213-214,
215
Extraskeletal osteosarcoma, 11, 123,
124, 179, 182-183
Extrauterine lipoleiomyoma, 29
Eyelids, 79
Fibrosarcoma, 10, 82, 98-101, 104-106,
137, 175, 226, 227, 231, 252, 266,
280, 289, 290, 296, 358, 361, 363,
364, 367
Fibrosarcoma, fibromyxoid type, 104
Fibrosarcoma of bone, 289
Fibrous dysplasia, 186, 187, 226, 228,
229, 265, 276, 278, 289, 338, 341-
342, 343, 350, 357, 358
Fibrous hamartoma of infancy,
10, 58-59, 85
Fibrous xanthoma, 120, 125, 292, 294
Fibroxanthoma, 109, 292, 312
Fibroxanthosarcoma, 120, 294
FKHR, 151, 152
Flexner-Wintersteiner rosette, 363
FLF, 134
FLI1, 172, 174, 299, 300, 321
FN1, 269
FNCLCC system, 15
FOS, 268, 344, 357
FUS, 42, 195, 215
F
Factor VIII, 77, 172
Factor XIIIa, 77, 99
Fallopian tube, 180
Familial adenomatous polyposis, 76,
350,
352-354
Familial expansile osteolysis, 350
Familial infiltrative fibromatosis, 352
Familial multiple polyposis, 352
Familial polyposis coli, 352
Fanconi anaemia, 365
Fetal rhabdomyoma, 143, 144
FGF2/FGFR1, 333
FGF3, 172
FGF4, 172
Fibroblastic osteosarcoma, 264, 266,
277, 287
Fibrochondroma, 180
Fibrolipomatosis, 24
Fibrolipomatous hamartoma, 19, 24
Fibroma of tendon sheath, 10, 66, 67
Fibromatosis colli, 10, 61-62
Fibronectin 1, 269
Fibroosseous pseudotumour of digits,
52
G
Ganglion cyst, 96, 188
Gardner fibroma, 10, 47, 75-76, 352
Gardner syndrome, 13, 76, 83, 98, 352,
353
GDP, 358
Genital leiomyoma, 11
Genital rhabdomyoma, 144
GFAP, 106, 142, 144, 145
Giant cell angioblastoma, 173
Giant cell angiofibroma, 10, 79, 87
Giant cell malignant pleomorphic fibrous
histiocytoma, 123-124
Giant cell reparative granuloma, 338
Giant cell sarcoma, 123
Giant cell tumour, 10, 13, 96, 109-114,
118, 123, 124, 226, 241, 262, 289,
291, 292, 309, 310-312, 313, 338
Giant cell tumour of low malignant
potential, 118
Giant cell tumour of soft tissue,
10, 118-119, 123, 124
Giant cell tumour of tendon sheath,
96, 109, 110-112
Giant marker chromosome, 37, 38, 46
422
Subject index
Giant osteoid osteoma, 262
Gigantism, 23, 161, 354
Glaucoma, 363
GLI, 37, 134, 151
Glomangioma, 136
Glomangiomatosis, 161
Glomangiomatosis, 136
Glomangiomyoma, 136
Glomus tumour, 11, 135, 136-137
Glomus tumours of uncertain malignant
potential, 136, 137
Glycogen synthase 3ß, 353
GNAS1, 187, 188, 342, 350, 357, 358,
359
GPCR, 358
Granulation tissue, 49, 92, 267, 322
Granuloma multiplex haemorrhagicum,
170
G
s
α
, 187, 358
GTP, 358
Gynaecomastia, 68
Hepatoblastoma, 352, 354
Hereditary chondrodysplasia, 234
Hereditary deforming osteochondro-
matosis, 234
Hereditary multiple exostoses, 234, 360
Hereditary osteochondromatosis, 234
Hernia, 68, 73, 189
Herringbone pattern, 98, 100, 182, 289,
296
HGF, 263
HHF-35, 61, 148
HHV8, see Human herpesvirus-8
Hibernoma, 10, 30, 33-34
High grade surface osteosarcoma,
282, 284-285
Histiocytosis X, 345 (see also
Langerhans cell histiocytosis)
Histocytoid haemangioma, 320
HIV lipodystrophy, 23
HMB45, 36, 106, 129, 195, 211, 212,
221, 222
HMGA1B, 22
HMGA2, 22, 93, 122, 190
HMGIC, 22, 37, 93, 107, 122, 190, 329
HMGIY, 22
Hobnail haemangioendothelioma,
165, 167
Hodgkin lymphoma, 306-308
HRAS, 122
hSNF5, 220
HSP90B, 269
Human herpesvirus-8, 91, 163, 170
Hyalinizing spindle cell tumour with
giant rosettes, 104
Hyperthyroidism, 357
Hypoglycemia, 89, 100, 354
Infantile fibromatosis, 26, 85, 98
Infantile fibrosarcoma, 10, 89, 98-100
Infantile haemangiopericytoma, 59, 60,
98, 135, 138, 139
Infantile lipoma, 26
Infantile myofibromatosis, 59, 89, 92, 98
Infiltrating angiolipoma, 28, 161
Inflammatory angiomatoid nodule, 159
Inflammatory fibrosarcoma, 91
Inflammatory liposarcoma, 35, 36
Inflammatory malignant fibrous histio-
cytoma, 125
Inflammatory myofibroblastic tumour,
10, 36, 77, 91-93, 125
Inflammatory myofibrohistiocytic
proliferation, 91
Inflammatory myxoid tumour of the soft
parts with bizarre giant cells, 96
Inflammatory pseudotumour, 91
INI1, 220
INT2, 172
Interleukin 6, 91
Intimal sarcoma, 131, 223-224
Intraabdominal desmoplastic small
round cell tumour, 216
Intracortical lipoma, 328
Intramedullary lipoma, 328
Intramuscular angiolipoma, 156
Intramuscular angioma, 156, 157
Intramuscular haemangioma, 13, 28,
156
Intramuscular myxoma, 11, 186-187,
188, 341, 350
Intraneural lipoma, 24
Intra-osseous counterpart of soft tissue
fibromatosis, 288
Intravascular bronchioloalveolar tumour,
173
Intravascular fasciitis, 48, 49, 92
Ischaemic fasciitis, 10, 47, 55-56
Ivory exostosis, 353
H
H19, 149, 354, 355
Haemangioblastoma, 175
Haemangioendothelial sarcoma, 322
Haemangioendothelioma, 11, 155, 163,
164, 165, 167, 168, 173, 174, 175,
319, 322
Haemangioma, 11, 13, 156-158, 159,
161, 163, 164, 168, 176, 177, 229,
320, 321, 322, 356
Haemangioma with Kaposi sarcoma-like
features, 163
Haemangiopericytoma, 9, 10, 47, 59,
60, 86, 88, 90, 98, 135, 138, 139
Haemangiopericytoma-like vessels,
87, 90
Haemangiosarcoma, 175, 322
Haemorrhagic osteosarcoma, 271
Hand-Schuller-Christian disease, 345
Haploinsufficiency, 361
HAS2, 26
h-caldesmon, 95, 130, 132
Hedgehog, 144, 357, 362
Helicase, 365, 367
Hemihypertrophy, 354, 355
I
Idiopathic multiple pigmented sarcoma
of the skin, 170
IGF2, 149, 350, 354, 355
IL-6, see Interleukin 6
Imprinting, 149, 354, 355
Inclusion body fibromatosis, 10, 64
Indolent myeloma, 302
Infantile digital fibroma, 64
Infantile digital fibromatosis, 64
J
Jansen metaphyseal chondrodysplasia,
357
Juvenile aponeurotic fibroma, 69
Juvenile bone cyst, 340
Juvenile fibrosarcoma, 98
Subject index
423
Juvenile hyaline fibromatosis, 10, 63-64
Juvenile nasopharyngeal angiofibroma,
352
Juxta-articular myxoma, 11, 188
Juxtacortical chondroblastic osteo-
sarcoma, 282
Juxtacortical chondroma, 239
Juxtacortical chondrosarcoma, 249, 282
Juxtacortical low grade osteosarcoma,
279
Juxtacortical osteosarcoma, 279, 284
Leiomyosarcoma, 11, 12, 14, 18,
120-124, 127, 131-134, 137,
224, 226, 325, 327
Leiomyosarcoma of bone, 325, 327
Leptin, 20
Letterer-Siwe disease, 345 (see also
Langerhans cell histiocytosis)
Leukaemoid reaction, 125
Leukocoria, 363
Li-Fraumeni syndrome, 13, 269, 349, 350
Lipid granulomatosis, 347
Lipoblast, 30
Lipoblastoma, 10, 26-27
Lipoblastomatosis, 10, 26-27
Lipofibroma, 24
Lipofibromatosis, 10, 26, 85
Lipogranulomatosis, 347
Lipoma, 10, 13, 20-22, 24, 26,
30, 31, 32, 33, 35, 36, 189,
226, 328, 329
Lipoma arborescens, 20
Lipoma of bone, 328-329
Lipoma-like liposarcoma, 35, 330
Lipomas, familial multiple, 350
Lipomatosis, 10, 13, 19, 23, 24,
25, 350
Lipomatosis of nerve, 10, 13, 19,
24-25
Lipomatosis, symmetrical, 350
Lipomatous haemangiopericytoma,
10, 69, 87, 90
Liposarcoma of bone, 330
Low grade central osteosarcoma,
275-276
Low grade endometrial stromal
sarcoma, 221
Low grade fibromyxoid sarcoma,
10, 47, 104, 105
Low grade intraosseous-type
osteosarcoma, 275
Low grade myofibroblastic sarcoma,
10, 47, 94-95
Low-grade intramedullary osteo-
sarcoma, 275
LPP, 22, 329
Lymphangioleiomyomatosis, 221
Lymphangioma, 11, 162, 167, 168,
172, 321
Lymphangiosarcoma, 175
Lysozyme, 121, 347
M
Macrodystrophia lipomatosa, 24
Macroglossia, 354
Madelung disease, 23
Maffucci syndrome, 175, 239, 240, 250,
350, 356
MAGE, 268
Male angiomyofibroblastoma-like
tumour, 73
Malignancy in giant cell tumour, 226,
313
Malignant angioendothelioma, 175
Malignant bone aneurysm, 271
Malignant endothelial papillary angio-
endothelioma, 167
Malignant epithelioid haemangioendo-
thelioma, 174
Malignant fibrous histiocytoma of bone,
294
Malignant fibrous histiocytoma, storiform
or fibroblastic type, 120
Malignant fibrous xanthoma, 120, 125,
294
Malignant giant cell tumour, 112, 114,
123, 272, 313
Malignant giant cell tumour of soft parts,
123
Malignant glomus tumour, 11, 136, 137
Malignant haemangioendothelioma, 175
Malignant histiocytoma, 294
Malignant lymphoma, 226, 231, 303,
306-308
Malignant melanoma of soft parts, 211
Malignant mesenchymoma, 11, 44, 132,
185, 215
Malignant osteoclastoma, 123
Malignant rhabdomyoma, 146
Mammary-type myofibroblastoma, 47, 68
MASL1, 122
Mazabraud syndrome, 186, 187, 341,
350, 358
McCune-Albright syndrome, 187, 341,
342, 350, 357-359
MCT1, 209
MDM2, 36, 37, 39, 45, 46, 122, 134,
151, 177, 263, 268, 272, 276, 281
Median nerve lipoma, 24
Mediastinum, 26, 35, 37, 44, 46, 77, 79, 86,
88, 91, 136, 156, 162, 163, 196, 208
K
Kaposi disease, 170
Kaposi sarcoma, 11, 13, 28, 158, 163,
170, 172, 175, 191, 303
Kaposi sarcoma, nodular, 172
Kaposi sarcoma, plaque, 172
Kaposiform haemangioendothelioma,
11, 163-164
Kaposi-like infantile haemangio-
endothelioma, 163
Kasabach-Merritt syndrome,
158, 163, 164
KCNQ1, 355
KCNQ1OT1, 354, 355
Kempson-Campanacci lesion, 343
Keratin, 51, 61, 72, 118, 124, 133, 160,
182, 197, 206, 219, 299, 333, 344
Ki-67, 177, 183, 305
KIT, 93, 127
Klippel-Trenaunay, 175
KRAB, 204
KRAS2, 172, 177, 268
L
Laminin, 95, 177
Langer Giedion syndrome, 360
Langerhans cell granulomatosis, 345
Langerhans cell histiocytosis, 226, 230,
345-346
Launois-Bensaude syndrome, 23
Ledderhose disease, 81
Leiomyoma, 11, 127, 128, 130, 226, 326
Leiomyoma of bone, 326
424
Subject index
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