CorsonPsychiatryGrandRounds.pdf

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TemplePsychiatryGrandRounds.ppt

Psychiatry

Grand Rounds

December 13, 2006

Neuropsychiatric

Manifestations of Tick

Borne Disease

Ann F Corson MD

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Infection and psychiatric illness

 “Recent immunologic, epidemiologic, microbiologic and

neuropsychiatric studies point to infectious etiologies of

several important neuropsychiatric disorders…several

infectious diseases including human influenza virus, HIV,

syphilis and Lyme disease are associated with

neuropsychiatric symptoms following transmission of

infectious agents to the central nervous system.

…evidence also points to potential for peri-, pre-, and

postnatal infections as causes for several

neurodevelopmental disorders.”

S. Hossein Fatemi, Ed., Neuropsychiatric Disorders and Infection

Taylor and Francis, 2005. ISBN 1 84184 520 5

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Infection and chronic illness

 “…infection may simply represent the first misstep along a

continuum from health to long-term illness and disability.”

 “…infectious agents likely determine more cancers,

immune-mediated syndromes, neurodevelopmental

disorders, and other chronic conditions than currently

appreciated.”

 “If a mere 5% of chronic disease is attributable to infectious

agents, in the US alone 4.5 million of the 90 million people

living with chronic disease might benefit from strategies

designed to prevent or appropriately treat selected

infections.”

O’Conner e al., Emerging Infectious Determinants of Chronic Diseases Emerg

Infect Dis 2006; 12(7): 1051-1057

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Tick bites

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Our three local ticks

Dog tick Dermacentor variabilis

Lone star tick

Amblyomma americanum

Deer tick Ixodes scapularis

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