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Nanotechnology in Drug Delivery
Biotechnology: Pharmaceutical Aspects
Volume I: Pharmaceutical Profiling in Drug Discovery for Lead Selection
R.T. Borchardt, E.H. Kerns, C.A. Lipinski, D.R. Thakker, B. Wang
Volume II: Lypophilization of Biopharmaceuticals
H.R. Constantino, M.J. Pikal
Volume III: Methods for Structural Analysis of Protein Pharmaceuticals
W. Jiskoot, D.J.A. Crommelin
Volume IV: Optimizing the ‘‘Drug-Like’’ Properties of Leads in Drug
Discovery
R.T. Borchardt, E.H. Kerns, M.J. Hageman, D.R. Thakker,
J.L. Stevens
Volume V: Prodrugs: Challenges and Rewards, Parts 1 and 2
V.J. Stella, R.T. Borchardt, M.J. Hageman, R. Oliyai, H. Maag,
J.W. Tilley
Volume VI: Solvent Systems and Their Selection in Pharmaceutics and
Biopharmaceutics
P. Augustijns, M.E. Brewster
Volume VII: Drug Absorption Studies: In Situ, In Vitro and In Silico
Models
C. Ehrhardt, K.J. Kim
Volume VIII: Immunogenicity of Biopharmaceuticals
M. van de Weert, E.H. Møller
Volume IX: Advances in Bioactivation Research
A. Elfarra
Volume X: Nanotechnology in Drug Delivery
M.M. de Villiers, P. Aramwit, G.S. Kwon
Nanotechnology in Drug
Delivery
Melgardt M. de Villiers
University of Wisconsin,
Madison, WI, USA
Pornanong Aramwit
Chulalongkorn University, Bangkok, Thailand
Glen S. Kwon
University of Wisconsin,
Madison, WI, USA
13
Editors
Melgardt M. de Villiers
University of Wisconsin
Madison, WI, USA
mmdevilliers@pharmacy.wisc.edu
Pornanong Aramwit
Chulalongkorn University
Bangkok, Thailand
Glen S. Kwon
University of Wisconsin
Madison, WI, USA
gskwon@pharmacy.wisc.edu
DOI: 10.1007/978-0-387-77667-5
e-ISBN: 978-0-387-77668-2
Library of Congress Control Number: 2008935894
# 2009 American Association of Pharmaceutical Scientists
All rights reserved. This work may not be translated or copied in whole or in part without
the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring
Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews
or scholarly analysis. Use in connection with any form of information storage and retrieval,
electronic adaptation, computer software, or by similar or dissimilar methodology now known
or hereafter developed is forbidden.
The use in this publication of trade names, trademarks, service marks, and similar terms, even
if they are not identified as such, is not to be taken as an expression of opinion as to whether or
not they are subject to proprietary rights.
While the advice and information in this book are believed to be true and accurate at the date
of going to press, neither the authors nor the editors nor the publisher can accept any legal
responsibility for any errors or omissions that may be made. The publisher makes no
warranty, express or implied, with respect to the material contained herein.
Printed on acid-free paper
springer.com
ISBN: 978-0-387-77667-5
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