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BioMEMS and Biomedical
Nanotechnology
Volume II
Micro/Nano Technology for Genomics
and Proteomics
BioMEMS and Biomedical
Nanotechnology
Mauro Ferrari, Ph.D. , Editor-in-Chief
Professor, Brown Institute of Molecular Medicine Chairman
Department of Biomedical Engineering
University of Texas Health Science Center, Houston, TX
Professor of Experimental Therapeutics
University of Texas M.D. Anderson Cancer Center, Houston, TX
Professor of Bioengineering
Rice University, Houston, TX
Professor of Biochemistry and Molecular Biology
University of Texas Medical Branch, Galveston, TX
President, the Texas Alliance for NanoHealth
Houston, TX
Volume II
Micro/Nano Technology for Genomics and Proteomics
Edited by
Mihrimah Ozkan
Dept. of Electrical Engineering
University of California, Riverside
Riverside, California USA
Michael J. Heller
Dept. of Bioengineering
University of California, San Diego
La Jolla, California USA
206609892.002.png
Mihrimah Ozkan
University of California, Riverside
Riverside, California
Michael Heller
University of California, Riverside
Riverside, California
Mauro Ferrari
Ohio State University
Columbus, Ohio
Library of Congress Cataloging-in-Publication Data
Volume II
ISBN-10: 0-387-25564-8
e-ISBN 10: 0-387-25843-4
Printed on acid-free paper.
ISBN-13: 978-0387-25564-4
e-ISBN-13: 978-0387-25843-0
Set
ISBN-10: 0-387-25661-3
e-ISBN:10: 0-387-25749-7
ISBN-13: 978-0387-25561-3
e-ISBN:13: 978-0387-25749-5
2006 Springer Science + Business Media, LLC
All rights reserved. This work may not be translated or copied in whole or in part without the written permission of
the publisher (Springer Science+Business Media LLC, 233 Spring Street, New York, NY 10013, USA), except for
brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information
storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now
known or hereafter developed is forbidden.
The use in this publication of trade names, trademarks, service marks and similar terms, even if they are not
identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to
proprietary rights.
987654321 SPIN 11407157
springer.com
C
Dedicated to Richard Smalley (1943–2005), in Memoriam
To Rick,
father founder of nanotechnology
prime inspiration for its applications to medicine
gracious mentor to its researchers
our light—forever in the trenches with us
(Rick Smalley received the 1996 Chemistry Nobel Prize
for the co-discovery of carbon-60 buckeyballs)
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