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doi:10.1016/j.nec.2008.04.001
Neurosurg Clin N Am 19 (2008) xi–xii
Preface
Andrew T. Parsa, MD, PhD
Guest Editor
The treatment of vestibular schwannoma is
optimally a collaborative effort between neuro-
surgeons and otolaryngologists. A multidisciplin-
ary approach is beneficial to the outcome of
management decisions that can range from serial
observations to surgical intervention. The advent
of more precise radiosurgery, with lower marginal
dosing, has ushered in a new era of treatment
paradigm.
This issue presents classic articles on treatment
for acoustic neuroma patients. The revelation in
these articles is that, as state-of-the-art of scientific
and clinical aspects of acoustic neuroma continue
to advance, the concepts of basic knowledge and
expert skill presented by our predecessors remain
central to the treatment of this disease.
Presentations of William House and Clough
Shelton’s middle fossa approach, Neal Cohen’s
retrosigmoid approach, Dale Brown and Ugo
Fisch’s transotic approach are as relevant and
useful to surgeons in 2008 as they were when
discussed a decade ago. Conservative manage-
ment of acoustic neuroma continues to develop
and is discussed here by Julian Nedzelski, David
Schessel, Andrew Pfleiderer, Edward Kassel, and
David Rowed. The cochlear and brainstem pre-
sentation has been updated with current concepts
by Elizabeth Toh and William Luxford. Selection
of surgical approach continues to be the crucial to
the outcome for the patient and is presented in
this issue with a timeless discussion by Robert
Jackler and Lawrence Pitts. More recent discus-
sions on surgical approaches and complications,
radiosurgery and radiotherapy, and stereotactic
radiation techniques are presented by our col-
leagues in otolaryngology, Marc Bennett and
David Haynes, Ilya Likhterov, Robert Allbright
and Samuel Selesnick, and Steven Abram, Paul
Rosenblatt, and Stephen Holcomb, respectively.
Absolutely essential information on microsurgical
anatomy, imaging, nerve monitoring, and guiding
patients through surgery are presented by Albert
Rhoton and Helder Tedeschi, Hugh Curtin and
William Hirsch, Charles Yingling and John
Gardi, and Douglas Backous and Huong Pham,
respectively. Through the words of these masters,
each of us is reminded of the depth and breadth of
their work, which continues to spur us on to
advance our skills and techniques and continue to
collaborate with each other. Collectively, we strive
to continually improve functional outcomes for
our patients with acoustic neuroma.
What does the future hold? The concept
that ‘‘the treatment of patients should be
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doi:10.1016/j.nec.2008.04.001
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xii
PREFACE
dictated by tumor biology’’ is a fundamental
tenet of oncology. However, we have yet to
embrace this completely in the realm of acoustic
neuroma. For example, patients who present
with small tumors or with minimal symptoms
are often treated empirically with surgery or
radiation as a pre-emptive measure, to prevent
growth and improve long-term function. Ongo-
ing studies into molecular attributes of tumors
that correlate with growth rate, or response to
radiation, should yield important insights into
what may be most appropriate for a particular
patient.
Once we gain insights into novel treatment
paradigms that better tailor our management,
how will we disseminate this information to
patients and providers? As with many diseases,
patient advocacy has played a critical role in this
regard. In particular, the Acoustic Neuroma
Association (ANA) serves as a model patient
advocacy group that has provided important
information for 25 years to its members.
The activities of the ANA include the
following:
1) The newsletter NOTES is published quar-
terly. ANA is committed to keeping its members
informed with professionally authored medical in-
formation, self-help aids, personal accounts from
acoustic neuroma patients, and support group
updates.
2) Patient booklets deal with all aspects of
acoustic neuroma. Single copies are free to mem-
bers; larger quantities may be purchased.
3) A national symposium is presented every
other year for acoustic neuroma patients, family
members, and health care professionals.
4) Local support groups provide opportunities
for patients to communicate and network with
others.
5) Research results are produced and pub-
lished on the effects of acoustic neuroma.
6) The Web site ( www.ANAUSA.org )s
maintained with an interactive ANA discussion
forum extending the goals of making information
and networking opportunities available to
patients.
The informed practitioner should be aware of
the landmark contributions in the field, stay up-
to-date on future directions for therapy, and be
able to refer patients to resources that facilitate
a better understanding of both.
Andrew T. Parsa, MD, PhD
Department of Neurological Surgery
Neurospinal Research Center and The Brain Tumor
Research Center
University of California San Francisco
505 Parnassus Avenue; M-779
San Francisco, CA 94143, USA
E-mail address: parsaa@neurosurg.ucsf.edu
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