Pharmacokinetics, Second Edition.pdf

Pharmacokinetics

DRUGS AND THE PHARMACEUTICAL SCIENCES

A SeriH of TfJxtbook, and Monograph,

Edittldby

J.m•• Sw.rbrick

School ofPharmllCY

University of North Carolina

Chapel Hill, North Carolina

Volume 1. PHARMACOKINETICS, Milo Gibaldi and Donald Perrier

(out ofprint)

Volume 2. GOOD MANUFACTURING PRACTICES FOR

PHARMACEUTICALS: A PLAN FOR TOTAL OUALITY

CONTROL, Sidney H. Willig, Murray M. Tuckerman, and

William S. Hitchings IV (out ofprint)

Volume 3. MICROENCAPSULATION, edited by J. R. Nixon (out of print)

Volume 4. DRUG METABOLISM: CHEMICAL AND BIOCHEMICAL

ASPECTS, Bernard Testaand Pettlr Jenner

Volume 5. NEW DRUGS: DISCOVERY AND DEVELOPMENT,

edited by Alan A. Rubin

Volume 6. SUSTAINED AND CONTROLLED RELEASE DRUG DELIVERY

SYSTEMS, edited by Joseph R. Robinson

Volume 7. MODERN PHARMACEUTICS, edited by Gilbert S.

Banker and Christopher T. Rhodes

Volume 8. PRESCRIPTION DRUGS IN SHORT SUPPLY: CASE

HISTORIES, Michael A. Schwartz

Volume 9. ACTIVATED CHARCOAL: ANTIDOTAL AND OTHER

MEDICAL USES, David O. Cooney

Volume 10. CONCEPTS IN DRUG METABOLISM (in two parts). edited

by Peter Jenner and Bernard Testa

Volume 11. PHARMACEUTICAL ANALYSIS: MODERN METHODS

(in two parts), edited by James W. Munson

Volume 12. TECHNIOUES OF SOLUBILIZATION OF DRUGS,

edited by Samuel H. Yalkowsky

Volume 13. ORPHAN DRUGS,edited by Fred E. Karch

Volume 14. NOVEL DRUG DELIVERY SYSTeMS: FUNDAMENTALS,

DEVELOPMENTAL CONCEPTS, BIOMEDICAL ASSESSMENTS,

Yie W. Chien

Volume 15. PHARMACOKINETICS, Second Edition, Revised and Expanded,

Milo Gibaldi and Donald Perrier

Other Volumes in Preparation

Pharmacokinetics

SECOND EDITION, REVISED AND EXPANDED

Milo Gibaldi

University of Washington

School of Pharmacy

Seattle, Washington

Donald Perrier

School of Pharmacy

University of Arizona

Tucson, Arizona

informa

healthcare

New York London

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